ANTIOXIDANT ACTIVITY OF HERBAL AGENT

DOI: https://doi.org/None
Issue: 
6
Year: 
2015

P.B. Lubsandorzhieva, PhD; T.A. Azhunova, PhD Institute of General and Experimental Biology, Siberian Branch, Russian Academy of Sciences; 5, M. Sakh’yamova St., Ulan-Ude 670047

Plant composition and its individual components, such as dry extracts from the leaves of stinging nettle (Urtica dioica L.), knotweed (Polygonum aviculare L.), and common yarrow (Achillea millefolium L.) and finely ground powders of ginger (Zingiber officinale, Roscoe.) rhizomes and Chinese cinnamon (Cinnamomum cassia L.) bark, have antioxidant activity in different in vitro test systems. The most effective activity is shown by dry Urtica dioica extract (Fe2+ chelating activity), water-soluble substances of Zingiber officinale (a superoxide radical binding agent), and Cinnamomum cassia (NO-binding and MDA-inhibitory activities). The antioxidant activity of an herbal agent has been borne out by in vivo experiments using a rat cytostatic disease model caused by intraperitoneal cyclophosphan injection. The plant composition in the animals receiving cyclophosphan was observed to enhance catalase and superoxide dismutase activities and to decrease malondialdehyde levels.

Keywords: 
stinging nettle (Urtica dioica L.)
knotweed (Polygonum aviculare L.)
common yarrow (Achillea millefolium L.)
ginger (Zingiber officinale
Roscoe.)
Chinese cinnamon (Cinnamomum cassia L.)
plant composition
antioxidant activity

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