Pharmacology as the basis for an interdisciplinary approach to the integrated drug assessment


G.N. Gildeeva(1), A.V. Belostotskiy(1), D.M. Andreevа(1), V.I. Iurkov(2) 1-I.M. Sechenov First Moscow State Medical University (Sechenov University); 8, Trubetskaya St., Build. 2, Moscow 119048, Russian Federation, 2-LTD «Medical Development Agency»; 1, Vasilisy Kozhinoi St., Moscow 121096, Russian Federation

Interdisciplinarity is a term expressing the integrative nature of the modern stage of scientific knowledge. During various stages of pharmacological science history its changes are substantially determined by a complex interaction of differentiation processes – the fall of a homogeneous, unified and integral system into a number of relatively autonomous areas and integration – combining previously independent subject areas, the emergence of «synthetic» disciplines. Pharmacology is a medical science that includes theoretical and experimental sections, as well as the experimental and clinical parts about patients, is interdisciplinary and involves close cooperation of specialists from different scientific fields. Due to historical reasons, each division works in its own separate direction, approves guidelines and guides, often without using the colleagues achievements. The interaction and mutual enrichment of various disciplines makes it possible to form a specialist who has vast theoretical knowledge and extensive practical skills, is able to successfully solve professional tasks, to carry out a differential diagnostic search, and provide medical care that fully meets modern standards


  1. Insel P.A., Amara S.G., Blaschke T.F., Meyer U.A. Introduction to the Theme «New Methods and Novel Therapeutic Approaches in Pharmacology and Toxicology». Annu. Rev. Pharmacol., 2017; 57: 13–7.
  2. Lötsch J., Ultsch A. Process Pharmacology: A Pharmacological Data Science Approach to Drug Development and Therapy. CPT Pharmacometrics Syst. Pharmacol., 2016; 5(4): 192–200.
  3. Aagaard-Hansen J., Ouma J.H..Int. J. Health Plann. Manage. Managing inter disciplinary health research--theoretical and practical aspects. 2002 Jul-Sep; 17 (3): 195-212.
  4. Robertson D.W., Martin D.K., Singer P.A. Interdisciplinary research: Putting methods under the microscope. BMC Medical Research Methodology, 2003; 3: 20.
  5. Reshenie Soveta Evrazijskoj ekonomicheskoj komissii ot 3 nojabrja 2016 g. № 89 «Ob utverzhdenii Pravil provedenija issledovanij biologicheskih lekarstvennyh sredstv Evrazijskogo ekonomicheskogo sojuza». [Decision of the EEC Council № 89 on November 03, 2016 «On the Approval of the Rules for Conducting Studies of Biological Medicines of the Eurasian Economic Union» (in Russian)].
  6. Anderson S.G. The collaborative research process in complex human services agencies: Identifying and responding to organizational constraints. Administration in Social Work, 2001; 25 (4): 1–19.
  7. Aram J.D. Concepts of interdisciplinarity: Configurations of knowledge and action. Human Relations, 2004; 57 (4): 379–412.
  8. Baba M.L., Gluesing J., Ratner H., Wagner K.H. The contexts of knowing: natural history of a globally distributed team. Journal of Organizational Behavior., 2004; 25 (5): 547–87.
  9. Frost S.H., Jean P.M. Bridging the disciplines: Interdisciplinary discourse and faculty scholarship. The Journal of Higher Education, 2003; 74: 119–49.
  10. Kenakin T., Bylund D.B., Toews M.L., Mullane K., Winquist R.J., Williams M. Replicated, replicable and relevant-target engagement and pharmacological experimentation in the 21-st Century. Biochem. Pharmacol., 2014; 87 (1): 64-77.
  11. Gil'deeva G.N., Belostotskij A.V. Nauchnoe konsul'tirovanie kak osnova dlja prinjatija reshenija po otsenke effektivnosti, bezopasnosti i kachestva vosproizvedennyh lekarstvennyh sredstv. Vestnik Roszdravnadzora, 2017; 2: 44–8. [Gildeeva G.N., Belostotsky A.V. Scientific consulting as a foundation for decision-making in assessing the efficiency, safety and quality of generic drugs. Vestnik Roszdravnadzora, 2017; 2: 44–8 (in Russian)].