Analysis of an extemporaneous formulation for the manufacture of solutions for electrophoresis

DOI: https://doi.org/10.29296/25419218-2022-04-08
Issue: 
4
Year: 
2022

K.A. Shubina, D.H. Shakirova, R.S. Safiullin
Kazan (Privolzhsky) Federal University, st. Kremlin, 18, Kazan, 420008, Russian Federation

Introduction: Currently, drug electrophoresis does not lose its relevance and is used for treatment, prevention, and rehabilitation after various diseases. A limited list of drugs is suitable for this procedure, due to the specifics of the impact of physical factors on the molecule of the substance and excipients introduced in the dosage form. Objective: to study and analyze the extemporaneous formulation for the manufacture of solutions for electrophoresis both for the population and for medical organizations using the example of a production pharmacy in Kazan, as well as to conduct a structural analysis of the market for substances used for the extemporaneous manufacture of solutions for electrophoresis. Material and methods: the State Register of Medicinal Products for 2022, invoices of medical organizations and prescriptions from the population received by the production pharmacy for the period from 2017 to 2021 were used as objects of study. The study used the methods of structural analysis, documentary research, content analysis. Results: A range of substances used for the manufacture of solutions for electrophoresis at the federal level was identified, which is represented by 16 INNs under 74 names of pharmaceutical substances, the main share of substances is produced in Russia (70.3%). An analysis of the extemporaneous formulation over the past 5 years has shown that the demand for electrophoresis solutions remains at a consistently high level, which indicates the relevance of the topic under study. Conclusion. As a result of the study, an up-to-date nomenclature list of pharmaceutical solutions for drug electrophoresis was formed.

Keywords: 
electrophoresis
extemporaneous production
substances
hospital need

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