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Schisandra chinensis leaves: the study of lignans using HPLC

DOI: https://doi.org/10.29296/25419218-2019-02-04
Issue: 
2
Year: 
2019

Iu.V. Dobrina, A.I. Slivkin Voronezh State University; 1, Universitetskaia Sq., Voronezh 394036, Russian Federation

Introduction. In medicine, the seeds and fruits of Chinense Schizandra are used to produce drugs that have a pronounced adaptogenic, antifatigue, stimulating and general tonic effect. Thin layer chromatography (TLC) showed that leaves of Schizandra Chinense used in traditional medicine have a similar composition of lignans with Schizandra Chinense seeds. Objective: HPLC study of lignans of Chinense Schizandra leaves harvested in the Voronezh Region. Materials and methods. Study subjects are dried leaves and fruits of Chinense Schizandra harvested in the Voronezh region. The analysis of lignans was carried out on an «Agilent 1260» liquid chromatograph with a diode-matrix detector using the method adapted to the analysis of lignans. Results. The content of schizandrin A in the leaves of Chinense Schizandra is almost the same as in seeds (83.43 mg / ml) and remains at the same level regardless of the plant vegetation phase. Conclusion. Leaves of Chinense Schizandra can be considered as an additional source of lignans.

Keywords: 
Chinense Schizandra
Schizandra chinensis (Turcz.) Ball.
leaves
HPLC
lignans
schizandrin A

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