Investigations on the development of a draft pharmacopoeia article on yellow iris (Iris pseudacorus) rhizomes: characteristics of identity

DOI: https://doi.org/10.29296/25419218-2019-05-05
Issue: 
5
Year: 
2019

E.A. Tikhomirova, A.A. Sorokina I.M. Sechenov First Moscow State Medical University (Sechenov University), 8, Trubetskaya St., Build. 2, Moscow 119048, Russian Federation

Introduction. Yellow iris (Iris pseudacorus L.) is widespread in the Russian Federation. The plant has a complex multicomponent composition of biologically active substances. However, the use of yellow iris rhizomes is very limited in Russian officinal medicine. The wider use of yellow iris rhizomes as a pharmaceutical plant substance and the design of innovative drugs require regulatory documentation that meets the current requirements for medicinal plant raw materials. Objective: to conduct in-depth morphological and anatomical studies of yellow iris rhizomes for the subsequent development of the draft pharmacopoeia article (PA) «Yellow iris rhizomes». Material and methods. The dried yellow iris rhizomes stored in the Shatura District, Moscow Region, in the summer of 2015 were investigated. The appearance and anatomical structure of the rhizomes were analyzed using the methods laid down in the State Pharmacopoeia of the Russian Federation, 14th edition (SP 14). Results. The investigators provide a refined and extended description of the appearance of yellow iris rhizomes of different processing forms (the rhizomes can be left whole, grounded, or powdered). Microscopic analysis made it possible to clarify their diagnostic signs characterizing whole raw materials and to visualize them. Conclusion. The findings of the in-depth morphological and anatomical studies of yellow iris rhizomes, which revealed their diagnostic signs, can be used in the development of a draft PA for raw materials.

Keywords: 
yellow iris
Iris pseudacorus L.
rhizomes
standardization
appearance
microscopy

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