MORINDA CITRIFOLIA IS A PROMISING MEDICINAL PLANT RAW MATERIAL FOR THE PRODUCTION OF HERBAL REMEDIES

DOI: https://doi.org/None
Issue: 
4
Year: 
2017

Professor I.E. Kaukhova, PhD; R.K. Agbadi; Professor S.A. Minina, PhD; A.U. Kutlushina Saint Petersburg State Chemopharmaceutical Academy; 14, Prof. Popov St., Saint Petersburg 197376, Russian Federation

Introduction. Morinda citrifolia or noni is a popular source for preparing traditional medicines in Pacific Islands. The main biologically active ingredients of Morinda citrifolia are phenolic and terpenoid compounds, organic acids, and alkaloids. Material and methods. The object of the investigation included dried leaves, fruits and roots of Morinda citrifolia, which had been gathered in Ghana. The biologically active substances of the studied raw materials were identified and their quality was assessed according to the standard pharmacopoeial methods described in the State Pharmacopoeia of the Russian Federation, XI and XIII editions). Results and conclusion. The content of basic groups of biologically active substances was phytochemically estimated. Alkaloids were found in the roots, leaves, and fruits. Anthraquinones were detected in the roots only. Tannic acids were found in the roots and leaves. The presence of flavonoids in all plant organs was confirmed, but most of them were in the roots. The merchandising and technological parameters of the analyzed herbal substances Morinda citrifolia fruit, leaves, and roots were established.

Keywords: 
Morinda citrifolia L.
Noni
product analysis
phytochemical analysis
roots
leaves
fruits

References: 
  1. Abbott, A. The geographic origin of the plants most commonly used for medicine by Hawaiians. J. Ethnopharmacol; 1985. 14: 213–22.
  2. Hirazumi A. Anticancer activity of Morindacitrifolia on intra-peritoneal implanted Lewis lung carcinoma in syngenic mice / Hirazumi, A., Furusawa, E., Chou, S.C., Hokama, Y. // Proceedings of the Western Pharmacological Society 37. 1994. P. 145–6.
  3. Wang M. Y. Cancer preventive effect of Morindacitrifolia (Noni) / Wang, M.Y., Su, C. // Annals of the New York Academy of Sciences 952. 2001. P.161–8.
  4. Pratibha, V. N. Anti-Diabetic Potential of Noni: The Yin and the Yang / Pratibha V. N., Phoebe W. H., Saksa E. // Molecules. – 2015. – R. 17684–719.
  5. Singh D. R. Morindacitrifolia L. (Noni): A review of the scientific validation for its nutritional and therapeutic properties / D. R. Singh // Journal of Diabetes and Endocrinology. – Vol. 3 (6) – 2012. – R. 78–85.
  6. Duduku K. Phytochemical Constituents and Activities of Morindacitrifolia L. / Duduku K., Rajesh N., Rosalam S. // 2. March 21, 2012. – P. 141–14
  7. Wang M. Y. Morindacitrifolia (Noni): a literature review and recent advances in Noni research / Wang, M.Y., West, B., Jensen, C.J., Nowicki, D., Su, C., Palu, A.K., Anderson, G., // Acta. PharmacologicaSinica. 23. 2002. P. 1127–41.
  8. Pratibha, V. N. Anti-Diabetic Potential of Noni: The Yin and the Yang / Pratibha V. N., Phoebe W. H., SaksaE. // Molecules. – 2015. – R. 17684–719.
  9. Vietnamese Pharmacopoeia Commission. 4th edition, 2010.
  10. Russian State Pharmacopoeia 13th edition. «Scientific Center of Expert Review of Medicinal Preparations- 2015.Tom 2. P.1004. [Gosudarstvennaya farmakopeya Rossiyskoy Federacii XIII izdaniya. // M.: Izdatel`stvo «Nauchnyy centr e`kspertizy sredstv medicinskogo primeneniya». 2015. T. 2. – 1004 s].
  11. USSR State Pharmacopoeia 1st edition. General Methods of Analysis. Min. Health USSR.11th edition. M. Medicine. 1987. P.336. [Gosudarstvennaya farmakopeya SSSR. Vyp. 1. Obshhie metody analiza / MZ SSSR. – 11-e izd. d. M. : Medicina, 1987. 336 s].
  12. Maltseeva A.A., Trineeva O. V, Chestikov A.C. Analysis of Flavonoids in Plants Using Thin Layer Chromatography Methods//Fharmatciya –2013.No1. P 13–6. [Mal`ceva, A.A. Tonkosloynaya hromatografiya v analize flavonoidov rastitel`nyh ob``ektov / A. A. Mal`ceva, O. V. Trineeva, A. S. Chistyakova i dr. // Farmaciya. – 2013. – № 1. – S. 13 6].
  13. Phytochemical and Product analyses of Medicinal Plant Samples. / ed. by L. S. Teslova. – 2nd ed, Rev. – SPb. PubSPCPA, 2008. – P. 168 [Fitohimicheskiy i tovarovedcheskiy analiz lekarstvennogo rastitel`nogo syr`ya: / pod red. L.S. Teslova. – 2-e izd, ispr. – SPb. : Izd-vo SPHFA, 2008. – 168 s.].
  14. Minina S.A. Chemistry and Technology of Phytopreparations/ Minina S.A., Kaukhova I. E. // M. GEOTAR-MED-2009-P.558.[ .Minina, S.A. Himiya i tehnologiya fitopreparatov / S.A. Minina, I.E. Kauhova // M: GE`OTAR-MED. – 2009 – 558 s.]