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A.A. Novikovа (1), P. Kezimana (1), A.I. Marakhova PhD, (1) E-mail:, Professor A.A. Sorokina (2), PhD 1-Institute of Biochemical Technology and Nanotechnology, People’s Friendship University of Russia; 6, Miklukho-Maklai St., Moscow 117198, Russian Federation; 2-I.M. Sechenov First Moscow State Medical University; 8, Trubetskaya St., Build. 2, Moscow 119991, Russian Federation

The paper presents procedures for preparing liposomal drugs and highlights the advantages and disadvantages of the existing methods. It considers the problems associated with technology of hydrophobic antioxidants (the low solubility and chemical stability of these pharmacological substances) and the advantages of liposomes for their delivery. The most promising technology for obtaining liposomes with drug substances having antioxidant properties has been ascertained to be a thin-film hydration method, followed by vocalization.

directed transport
thin-film hydration method

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