YELLOW IRIS (IRIS PSEUDACORUS L.) RHIZOMES: ANTIMICROBIAL ACTIVITY

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DOI: https://doi.org/None
Issue: 
7
Year: 
2017

E.A. Tikhomirova (1); Professor A.A. Sorokina (1), PhD; A.I. Marakhova (2), PhD 1-I.M. Sechenov First Moscow State Medical University; 2, B. Pirogovskaya St., Build. 4, Moscow 119991, Russian Federation; 2-Institute of Biochemical Technology and Nanotechnology, People’s Friendship University of Russia; 6, Miklukho-Maklai St., Moscow 117198, Russian Federation

Introduction. The growing drug resistance of microorganisms necessitates the search for effective and safe agents for the treatment of infectious diseases. Of interest in this regard are medicinal plant drugs. Yellow iris (Iris pseudacorus L.) rhizomes are widely used in folk medicine to treat infectious diseases. Objective: to investigate the antimicrobial activity of raw yellow iris material. Materials and methods. The investigation object was the dried yellow iris rhizomes gathered in the Moscow Region. The antimicrobial activity of the raw material was studied by an agar diffusion test in accordance with the procedures given in the State Pharmacopoeia of the Russian Federation, 13th Edition. Aqueous and hydroalcoholic extracts from the raw materials were applied. Results. The yellow iris rhizome extracts were shown to have different antimicrobial activities. The aqueous extract was found to inhibit yeast growth; the hydroalcoholic extract had an inhibitory effect on the growth of gram-positive and gram-negative microorganisms and yeasts. Conclusion. It was experimentally confirmed that the extracts from yellow iris rhizomes had antimicrobial activity against gram-positive and gram-negative bacteria and yeasts.
Keywords: 
yellow iris
Iris pseudacorus L.
rhizomes
antimicrobial activity
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