EQUINE SKIN COLLAGEN IS A NEW ADJUVANT

DOI: https://doi.org/None
Issue: 
2
Year: 
2015

Professor L.P. Istranov, PhD; E.V. Istranova, PhD Research Institute of Molecular Medicine, I.M. Sechenov First Moscow State Medical University; 8, Trubetskaya St., Build.2, Moscow 119991

The investigation of the chemical and amino acid composition of alkaline-treated equine skin collagen and the physicochemical properties of its derived acetous solutions showed their identity with the much used solutions of alkaline-treated bovine skin collagen. The findings suggest that equine skin collagen may be used as an adjuvant and may replace bovine skin collagen in the technology of collagen preparations and medical products.

Keywords: 
adjuvant
collagen
equine skin
properties

References: 
  1. Chvapil M., Kronenthal R.L., Winkle W.V. Inter. Review of Connect. Tis. Res., 1973; 6: 11–61.
  2. Chvapil M., J.Biomed. Mater.Res., 1982; 16: 245–263.
  3. Kollagenoplastika v medicine (pod red. V.V Kovanov, I.A. Sychenikov). M.: Medicina, 1976. [Collagenoplasty in medicine (ed. V.V. Kovanov, I.A. Sychenikov). Moscow: Medicine,1976 (in Russian)].
  4. Shirshakova M. Zhurnal prikladnoy e`stetiki, 2006; 1. (2): 96–100. [Shirshakova M. Journal of applied aesthetics, 2006; 1. (2): 96–100 (in Russian)].
  5. Parentean-Bariel R., Gauvin R., Berthod F., Materials, 2010; 3: 1863–1887.
  6. Khan R., Khan V.N., Bee A. Biology and Medicine, 2011; 3.(4): 25–32.
  7. Egorova M., Zhurnal prikladnoy e`stetiki, 2006; 1. (2): 110–112. [Yegorova M., Journal of applied aesthetics, 2006; 1. (2): 110–112 (in Russian)].
  8. Edelmann-Grill B., Ottok S., Arzneim-Forsch. Drug Res., 1987; 37(11), 7: 802–808.
  9. Istranov L.P., Istranova E.V., Sychenikov I.A. Farmaciya, 1984; 5: 76. [Istranov L.P., Istranova E.V., Sychenikov I.A. Farmatsiya, 1984, 5, 76 (in Russian)]