INFRARED SPECTROPHOTOSCOPIC DETERMINATION OF THE IDENTITY PET AND C-PET SUBSTANCES

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DOI: https://doi.org/None
Issue: 
4
Year: 
2015

N.E. Novozhilova (1); N.N. Kutina, PhD (1*); O.A. Petukhova (1); Professor Yu.Ya. Kharitonov (1), PhD 1 -Medbiofarm RPC, Obninsk 2 -I.M. Sechenov First Moscow State Medical University; 8, Trubetskaya St., Build.2, Moscow 119991

The compounds 2-phenethyldithiocarbamoyl acetic acid (PET) and its dehydrated cyclic form (C-PET) belong to a group of isothiocyanates, natural compounds that can inhibit carcinogenesis or tumorigenesis. Analysis of the infrared absorption spectra of PET and C-PET samples showed their specificity for each substance. The spatial structure of C-PET substance has been confirmed by a direct X-ray structural study of its molecular and crystal structure. The spectral characteristics obtained could characterize the molecular structure of C-PET, Relying on an investigation of the infrared spectra of PET and C-PET substances, the authors have proposed a test to determine their identity.
Keywords: 
2-phenethyldithiocarbamoyl acetic acid (PET)
dehydrated cyclic form of PET (C-PET)
infrared spectra
identity
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