USE OF CURRENTLY AVAILABLE BASE-FORMING SUBSTANCES IN THE TECHNOLOGY OF SOFT FORMULATIONS: THE PRESENT STATUS AND PROMISES

DOI: https://doi.org/None
Issue: 
6
Year: 
2015

M.A. Dzhavakhyan, PhD; A.V. Davydova; S.P. Komkova; O.A. Semkina, PhD All-Russian Research Institute of Medicinal and Aromatic Plants; 7, Grin St., Building 1, Moscow 117216

The rationally chosen base in soft formulations optimizes a drug manufacturing process, sets up parameters for active ingredient release, imparts drug stability, and on its own carries properties, such as softening, exudative, reparative, and others, etc., which are necessary for an end product. A range of currently available bases for the manufacture of soft formulations is considered. The most popular gelling agents, such as polymer hydrogels - carbomers, poloxamers, cellulose esters, and liposomal hydrogel, are characterized.
Keywords: 
soft formulation
excipients
gel
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