DETERMINATION OF LIDOCAINE HYDROCHLORIDE AND MENTHOL AS PART OF HANDELIA GEL

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DOI: https://doi.org/None
Issue: 
1
Year: 
2016

M.M. Ziyamukhamedova, PhD; Professor Z.A. Nazarova, PhD Tashkent Pharmaceutical Institute; 45, Aibek St., Tashkent 100015, Uzbekistan

Liquid extract of Handelia trichophylla (Schrenk) Heimer flowers was used to develop gel technology for the treatment of periodontitis. The gel contains liquid extract of Handelia trichophylla, lidocaine hydrochloride, menthol, carboxymethyl cellulose sodium salt, glycerol, and purified water. To standardize the proposed formulation, procedures were developed to quantify lidocaine hydrochloride (high performance liquid chromatography) and menthol (chromatography-mass spectrophotometry) in the gel.
Keywords: 
Handelia trichophylla (Schrenk) Heimer
liquid extract
gel
lidocaine hydrochloride
menthol
high performance liquid chromatography
chromatography-mass spectrophotometry
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