METHODOLOGICAL BASES FOR REVEALING THE SPECIFIC FEATURES OF PHARMACEUTICAL CARE TO PREGNANT WOMEN WITH HYPOTHYROIDISM

DOI: https://doi.org/None
Issue: 
5
Year: 
2016

Professor G.T. Glembotskaya, PhD; A.S. Zakharova I.M. Sechenov First Moscow State Medical University; 8, Trubetskaya St., Build. 2, Moscow 119991, Russian Fedration

Background. Thyroid dysfunctions lead to pregnancy and labor complications and other gynecological problems in women. Objective: to comparatively characterize clinical guidelines in order to form the methodological bases for revealing the specific features of pharmaceutical care to pregnant women with hypothyroidism. Material and methods. The clinical guidelines of the American Thyroid Association, the USA Endocrine Society, the European Thyroid Association, and the Federal Clinical Guidelines for the Diagnosis and Treatment of Thyroid Diseases in Pregnant Women were studied using a content analysis and a comparative analysis. Results. The authors have formed main criteria that were used to comparatively characterize the documents analyzed. Recommendations for the treatment of hypothyroidism in pregnant women are presented in all the documents, but the emphases placed in them are rather widely differentiated. Replacement therapy using different L-T4 dosages is the current standard of treatment for hypothyroidism. Conclusion. The methodological bases were formed to reveal the specific features of pharmaceutical care to pregnant women with hypothyroidism. The study results may be used by pharmacists, practitioners, and investigators in optimizing medical and pharmaceutical care to pregnant women with thyroid pathology.

Keywords: 
clinical guidelines
pharmaceutical care
hypothyroidism
pregnancy

References: 
  1. Autoimmune Thyroid Disease in Pregnancy: A Review Juan C. Galofre, M.D., Ph.D.1,,2 and Terry F. Davies, M.D. 12014.
  2. Dreval` A.V., Shestakova T.P., Nechaeva O.A. Osobennosti lecheniya zabolevaniy shhitovidnoy zhelezy u beremennyh. Lechashhiy vrach, 2008; 10: 32–5.
  3. Glembockaya G.T., Zaharova A.S. Obosnovanie neobhodimosti i vozmozhnostey optimizacii farmacevticheskoy pomoshhi zhenshhinam s patologiey shhitovidnoy zhelezy. Farmaciya i farmakologiya, 2015; 4 (11): 37–42.
  4. Korzhavyh E`.A., Ovod A.I., Dremova N.B. Osnovy farmacevticheskoy pomoshhi v zdravoohranenii. Kursk: KGMU, 2009; 412.
  5. Glembockaya G.T., Maskaeva A.R. Integraciya deyatel`nosti provizora i vracha v obespechenii e`ffektivnosti i bezopasnosti lekarstvennoy terapii. Farmateka, 2001; 4: 24–31.
  6. Kozub O.V., Glembockaya G.T. Sociologicheskaya ocenka indikatorov kachestva farmacevticheskoy pomoshhi pacientam golovnoy bol`yu. Farmaciya, 2012; 2: 11–2.
  7. Kozub O.V., Glembockaya G.T. Vyyavlenie vozmozhnyh bar`erov sovremennoy i e`ffektivnoy farmacevticheskoy pomoshhi
  8. pacientam s golovnoy bol`yu.Novaya apteka: aptechnyy assortiment: Zhurn. dlya rukovoditeley i specialistov pervogo stola, 2012; 2:18–21.
  9. Glembockaya G.T., Kozub O.V. Farmacevticheskaya pomoshh` bol`nym migren`yu i golovnoy bol`yu napryazheniya: upravlenie potrebitel`skoy cennost`yu. Farmaciya, 2015; 7: 27–9.
  10. Fadeev V.V. Po materialam klinicheskih rekomendaciy Evropeyskoy tireoidnoy associacii po diagnostike i lecheniyu subklinicheskogo gipotireoza u beremennyh zhenshhin i detey. Klin. i e`ksper. tireoidologiya, 2014; 10 (3): 20–6.
  11. Troshina E.A., Sviridenko N.Yu., Vanushko V.E`. i dr. Federal`nye klinicheskie rekomendacii po diagnostike lecheniyu tireotoksikoza s diffuznym zobom (diffuznyy toksicheskiy zob, bolezn` Greyvsa–Bazedova), uzlovym/ mnogouzlovym zobom. M., 2014.
  12. Fadeev V.V. Po materialam klinicheskih rekomendaciy E`ndokrinologicheskogo obshhestva SShA po diagnostike i lecheniyu zabolevaniy shhitovidnoy zhelezy vo vremya beremennosti. Klin. i e`ksper. tireoidologiya, 2012; 8 (4): 8–17.
  13. Fadeev V.V. Po materialam klinicheskih rekomendaciy po diagnostike i lecheniyu zabolevaniy shhitovidnoy zhelezy vo vremya beremennosti i v poslerodovom periode Amerikanskoy tireoidnoy associacii. Klin. i e`ksper. tireoidologiya, 2012; 8 (1): 7–18.
  14. Dzh. Merta. Spravochnik vracha obshhey praktiki. M.: Praktika, 1998; 1180.
  15. Kornyushin V.Yu. Standarty nadlezhashhey aptechnoy praktiki: mirovoy opyt, vnedrenie v Rossii. Farm. vest., 2011; 32.