Development of technology and study of the microbiological purity of dental gel

DOI: https://doi.org/10.29296/25419218-2023-01-04
Issue: 
1
Year: 
2023

N.M. Rizaeva(1), N.A. Yunuskhodjaeva(2), R.A. Khusainova(2), N.E. Yunuskhojieva(2),
1-Tashkent Research Institute of Vaccines and Serums, Republic of Uzbekistan, 100084, Tashkent, Chingiz Aytmatov St., 37.
2-Tashkent Pharmaceutical Institute, Republic of Uzbekistan, 100015, Tashkent, Aibek St., 45.

Introduction. The development of herbal medicines is an important part of the pharmaceutical industry. Among the common flavonoid-containing plants there are the herb of knotweed pepper, the herb of knotweed bird and the nettle. From these plants, a liquid extract was obtained for a hemostatic effect. Objective of the study. To develop a gel technology from local plant raw materials liquid extract and study the microbiological purity. Material and methods: the object of the study was a dental gel that meets the requirements of regulatory documents. Determination of microbiological purity was carried out in accordance with the methodology of the SP XI edition. Results. The technology of dental gel from a liquid extract obtained on the basis of local vegetable raw materials was experimentally established. Conclusion. The data on the substantiation of the composition, technology, the choice of the type and amount of preservative to stabilize the gel in the studied storage period are presented. Study of the antimicrobial, wound-healing properties of dental gel based on liquid extract was carried out.

Keywords: 
dentistry
gel
liquid extract
technology.

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