Development of technology for obtaining a dry extract from the Scutellaria Iscanderi Juz. herb

DOI: https://doi.org/10.29296/25419218-2023-04-05
Issue: 
4
Year: 
2023

Sh.Kh. Muratova(1), M.G. Ismailova(2), P.L. Ismailova(1), R.M. Khalilov(3)
1-Uzbek Research Chemical-Pharmaceutical Institute named after A. Sultanov, Do’rmon yo’li str, 40, Tashkent, 100125, Uzbekistan;
2-Tashkent Pharmaceutical Institute, Oybek str, 45, Tashkent, 100015, Uzbekistan;
3-Institute of Chemistry of Plant Substances named after Academician S.Yu. Yunusov of the Academy of Sciences of the Republic of Uzbekistan, Mirzo Ulugbek str, 77, Tashkent, 100170, Uzbekistan

Introduction. Plants of the genus Scutellaria L. are widely used in medicine in the treatment of various diseases. One of the common species of the genus Scutellaria L. in Uzbekistan is Scutellaria Iscanderi Juz., which contains flavonoids, tannins and has an effective sedative effect. Objective: to develop an optimal technology for the production of dry extract from the S. Iscanderi herb. Material and methods. The object of the study is the S. Iscanderi herb, as well as liquid and dry extracts based on it. Determination of technological parameters of the extraction process was carried out in accordance with well-known methods. The quantitative content of the sum of flavonoids was determined by the spectrophotometric method, the content of tannins was determined by the method of volumetric permanganometric titration. Results. A technology has been developed for obtaining a dry extract from the S. Iscanderi herb. The optimal extractant and extraction conditions were experimentally established. Conclusion. The data on the substantiation of the technology for obtaining a dry extract from the S. Iscanderi herb is presented.
Keywords: 
Scutellaria Iscanderi Juz.
flavonoids
tannins
extractives
extraction
drying
technology
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