The current state of knowledge of Ethiopian sage (Salvia aethiopis L.)

DOI: https://doi.org/10.29296/25419218-2023-05-01
Issue: 
5
Year: 
2023

A.A. Krymova, O.I. Popova
Pyatigorsk Medical and Pharmaceutical Institute – a branch of Volgograd State Medical University, Kalinin Avе., 11, Pyatigorsk, 357532, Russian Federation

Introduction. Currently, preventive measures aimed at preserving and strengthening human health are becoming increasingly important in medicine and pharmacy. Phytotherapy has been and remains an important area of preventive measures, therefore, the expansion of supply and availability of medicinal plant raw materials and identification of alternative plant sources of biologically active substances make it possible to use it on a wider scale with more efficiency to improve the public health. Objective: The purpose of the study is to analyze and generalize the available information about Ethiopian sage (Salvia aethiopis L.), which is of interest due to its potential for wider use as a medicinal plant raw material. Material and methods. Data on the distribution area, phytochemical composition, pharmacological activity, and use of Ethiopian sage (Salvia aethiopis L.) in folk medicine are obtained from online databases, foreign pharmacopoeias, scientific journals, monographs, and a number of other literary sources. Results. Ethiopian sage is widely used in folk medicine to treat tuberculosis, heart failure, hemoptysis. We know of antibacterial properties of Ethiopian sage root extract. Terpenes predominate in the chromatographic profile of the essential oil of the plant, their pronounced anti-inflammatory and bactericidal activity has been established. The extract of the aboveground parts of Ethiopian sage partially inhibits opioid and cannabinoid receptors. The plant was previously included in the USSR State Register of medicinal plants raw material and was used in phytotherapy as part of the M.V. Zdrenko’s blend. However, the contemporary information about this type of sage needs updating. It is necessary to update normative documents and instructions for harvesting raw materials for its introduction into pharmaceutics. Conclusion. An in-depth pharmacognostic study of Ethiopian sage will make it possible to characterize it as a pharmaceutical substance of plant origin, develop standardization methods, and justify the areas and volumes of raw material procurement.
Keywords: 
еthiopian sage
Salvia aethiopis L.
phytotherapy
essential oils
terpenes
flavonoids.
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