Antimicrobial activity of yarrow essential oil fractions

DOI: https://doi.org/10.29296/25419218-2023-06-04
Issue: 
6
Year: 
2023

E.E. Savelyeva, A.A. Efremov, N.A. Bulgakova, T.V. Rukosueva, V.A. Volkova
FSBEI НЕ Prof. V.F. Voino-Yasenetsky KrasSMU MOH Russia, Partizan Zheleznyak str., 1, Krasnoyarsk, 660022, Russian Federation

Introduction. Essential oils of plants have a complex multicomponent composition, which determines their diverse application. The main pharmacological action, including antimicrobial properties, of essential oils most often determines the component that is in a larger amount. With the presence of chamazulene, which can accumulate in the essential oil of yarrow in a significant amount, the anti-inflammatory, bactericidal, anti-allergic, wound-healing effect of the oil is associated. The content of chamazulene in oil depends on the place where the plant grows. Objective: to study the antimicrobial activity of individual fractions of the essential oil and the individual compound chamazulene of the common yarrow growing in the Krasnoyarsk region. Material and methods. The essential oil from the aerial part of the common yarrow was isolated by exhaustive hydrosteam distillation. The component composition of the extracted oil was established earlier. Antimicrobial activity was determined by the disk diffusion method. Results. The antimicrobial activity of the essential oil of yarrow, its individual fractions and individually isolated substance chamazulene against strains of Staphylococcus aureus (MSSA), Staphylococcus aureus (MRSA), Escherichia coli, Pseudomonas aeruginosa and Candida albicans was studied. The strains of Escherichia coli and Pseudomonas aeruginosa proved to be insensitive to the action of essential oil and its fractions. Against strains of Candida albicans, Staphylococcus aureus (MSSA) and Staphylococcus aureus (MRSA), oil showed lower bactericidal activity compared to fractions enriched in chamazulene. The resistant strain of Staphylococcus aureus (MRSA) turned out to be the most sensitive to individual chamazulene, the strain of Pseudomonas aeruginosa showed resistance. Conclusion. The most pronounced antimicrobial effect of yarrow essential oil, its fractions and the individual substance chamazulene was obtained against staphylococci.
Keywords: 
yarrow
Achillea millefolium L.
essential oil
antimicrobial activity.
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