Analysis of cases of adverse drug reactions in pediatrics

DOI: https://doi.org/10.29296/25419218-2024-04-07
Issue: 
4
Year: 
2024

E.A. Egiazaryan, I.V. Kosova, M.M. Kurashov, L.I. Sotnikova
People's Friendship University of Russia named after Patrice Lumumba, Mikluho-Maclaya st., 6, Moscow, 117198, Russian Federation

Introduction. Due to the fact that prescribing medications to pediatric patients is potentially associated with an increased risk of adverse reactions (AR) or lack of therapeutic efficacy, monitoring the effects of pharmacotherapy in the post-registration period in this group of patients is of particular interest. Many drugs prescribed to children are not approved for use in pediatrics, and there is insufficient evidence of their safety and effectiveness in this population. Detection and analysis of signals in pediatric practice is a very time-consuming process. The spontaneous reporting system organized in medical organizations will allow obtaining new information about the safety of drug use by pediatric patients and developing measures to reduce the risks associated with pharmacotherapy. Objective: to analyze cases of adverse reactions in the use of drugs in pediatrics, identified by medical professionals. Material and methods. Sociological study, which was attended by 70 doctors working in children's clinics in Moscow. An original questionnaire containing 20 questions was developed for the study. Results. The results obtained indicate that progress in the treatment of children can’t be achieved without improving the pharmacovigilance system in reporting cases of adverse reactions in medical organizations. Conclusion. A significant contribution to the solution of this problem can be made by healthcare workers by timely informing the authorized pharmacovigilance authorities about the complications of pharmacotherapy in pediatric patients.
Keywords: 
adverse reactions
children
reporting
survey of healthcare workers.
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