IMPROVEMENT OF INDICATORS OF THE QUALITY OF BISTORT (POLYGONUM BISTORTA L.) RHIZOMES

Introduction. In accordance with modern requirements for normative documents on raw medicinal plant materials, the current pharmacopoeial article on bistort (Polygonum bistorta L.) rhizomes needs to be improved. Objective: to establish the amount of whole and ground bistort rhizomes for inclusion in the draft monograph on its raw materials. Material and methods. The investigation objects were the samples of raw materials (whole ones) collected in the Leningrad Region in 2008 to 2014 and their industrial (serial) samples in packs (ground raw materials). Their numerical values were determined in accordance with the general pharmacopoeial articles of the State Pharmacopoeia of the Russian Federation, XIII edition. Results. Parameters, such as tannin contents; moisture content; total ash; 10% hydrochloric acid-insoluble ash; the content of rhizomes blackened at the fracture; the levels of pieces of roots, leaves, and stems; those of organic and mineral impurities, were determined for whole and ground bistort rhizomes and their reference values were also established. Conclusion. The values characterizing the quality of whole and ground raw medicinal plant materials were determined for bistort rhizomes. These are included in the section «Tests» of the draft monograph on raw materials.