VALIDATION OF SPECTROPHOTOMETRIC PROCEDURE FOR QUANTIFICATION OF VINPOCETINE IN MICROCAPSULES

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DOI: https://doi.org/None
Issue: 
5
Year: 
2015

Yu.A. Polkovnikova, PhD; V.F. Dzyuba, PhD; E.N. Melnikova; N.P. Selina Voronezh State University; 1, Universitetskaya Square, Voronezh 394006

A procedure for spectrophotometric estimation in the ultraviolet region at a wavelength of 314±2 nm has been developed to quantify the content of vinpocetine in the microcapsules. Validation studies have shown that the developed procedure is characterized by specificity, adequate accuracy (RSD = 2.898%), precision in all concentration ranges (RSD = 2.75%), and a linear relationship (correlation coefficient (R) = 0.9964). The procedure may be properly reproduced and appropriate to make a further application.
Keywords: 
vinpocetine
ultraviolet spectrophotometry
microcapsules
validation
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